Semi-Daonil review: uses, contraindications, dosage & side effects

Today, the number of people suffering from diabetes exceeds 300 million people worldwide, and this number is constantly growing. According to experts, in 10 years the number of patients may increase by 1.5 times. Many people on the planet do not even suspect that they already have this dangerous disease, so the total number of cases can be much higher. Diabetes kills gradually and ruthlessly. If the patient does not undergo treatment and does not take care of his health, then very soon he will have dangerous complications, for example, loss of vision, destruction of blood vessels, amputation of limbs or failure of internal organs. Elevated glucose does not cause concern only at the very beginning of the disease. The last stage of this disorder is always tragic. Today, many pharmacological companies are developing new tools to combat this dangerous ailment. Semi-Daonil is one of them. We will tell you the truth about this antidiabetic drug.


Semi-Daonil is an effective antidiabetic drug developed by the Indian pharmaceutical company Aventis Pharma. The drug has a high hypoglycemic property, quickly returning blood sugar levels to the required range. Doctors recommend the drug as monotherapy or an additional hypoglycemic agent in the treatment of non-insulin-dependent diabetes (type 2). Semi-Daonil has been proven to successfully enhance the effectiveness of a diabetic diet. During prolonged use, the glucose level stabilizes, returning the patient to a normal state. The main active ingredient of the drug is Glibenclamide. It acts on the pancreas, stimulating the body to produce insulin. This hormone is necessary for energy metabolism in the body.

Dosage form

Semi-Daonil release form

Aventis Pharma produces Semi-Daonil in the form of small round white tablets. Each pill contains 2.5 mg of the active substance. Tablets are packaged in blisters. They are located in cardboard packaging. The volume of the Glibenclamide varies from 100 to 800 pcs. in one package.

What are the components of Semi-Daonil?

Semi-Daonil consists of several components. The main active ingredient is Glibenclamide, its amount is 2.5 mg. Other ingredients are auxiliary. They form the shell of the tablet and do not pose a threat to human health. For instance:

  • microcrystalline cellulose
  • magnesium stearate
  • lactose monohydrate

How to take this drug?

Self-treatment of diabetes is unacceptable. Be sure to consult a doctor and strictly follow his recommendations. Typically, endocrinologists begin treatment for type 2 diabetes with a minimum daily dosage. It is 2.5 – 5 mg. The patient should take Semi-Daonil orally with a large amount of water. Tablets should be used before the first meal. You should take the entire volume of the drug at once. If the Glibenclamide did not give a result, then its volume must be adjusted. It is safe to increase the dose of Semi-Daonil by 2.5 mg per day for 1 week. In doing so, you should monitor changes in blood glucose levels. Once it reaches acceptable values, you will determine your daily dosage. Such manipulations with the Glibenclamide should be carried out under the supervision of the attending physician. The maximum daily dosage that is not recommended to be exceeded is 20 mg. When using Glibenclamide in a volume of more than 10 mg, the dose should be divided by 2 times. The first reception should be done at breakfast, and the second at dinner. The effectiveness of the Glibenclamide increases with regular use at the same time. When skipping a dose, do not double the dose of the medicine.


Semi-Daonil contraindications

Semi-Daonil has established itself as a highly effective medicine suitable for a large number of patients. Doctors prescribe Glibenclamide in many cases when other hypoglycemic drugs do not cope with their function. However, Glibenclamide has several contraindications for use:

  • Acute renal or liver failure
  • Insulin-dependent diabetes (type 1)
  • Pregnancy
  • Younger age 18 or over 65 years old

In other cases, Semi-Daonil successfully treats patients and helps prevent the development of dangerous complications. It is worth noting that clinical trials did not reveal the presence of Glibenclamide in mother’s breast milk, so it can be used during breastfeeding. However, a woman should additionally consult a doctor so that he can weigh the risks and prescribe the right therapy.

Side Effects of Semi-Daonil

Like any medical product, Semi-Daonil can cause negative symptoms. Clinical studies have shown that the likelihood of their occurrence is extremely small. According to statistics, most often doctors register the following side effects:

  • Nausea
  • Vomiting
  • Dizziness
  • Heartburn
  • Diarrhea
  • Stomach ache
  • Itching
  • Skin rash
  • Photosensitivity

If you feel the first signs of side effects, stop taking Glibenclamide. Additional consultation with your doctor will be the right decision. Only a specialist will be able to determine the cause of the negative manifestations and prescribe a safer course of treatment.

Interaction with other medicines

Various medications may affect the hypoglycemic effectiveness of Semi-Daonil. They are more likely to reduce the benefits of using this antidiabetic drug, so before using several drugs, you should consult an endocrinologist. Only an experienced specialist will be able to determine the safety of their use.

Storage conditions

The manufacturer recommends storing Semi-Daonil in a dark and warm place, without moisture. The shelf life of the Glibenclamide is 2 years. During this time, you can safely use the tablets, however, after two years. The drug should be disposed of. Using expired Glibenclamide may be harmful to your health.

Leave a Reply