Glyset review: uses, dosage and other facts

What is the chance of getting diabetes? Few people think about it, but this danger threatens almost everyone. An improper diet with a lot of sweets and carbonated drinks, fast food, a sedentary lifestyle and constant stress lead to the accumulation of extra pounds. The level of glucose in the blood gradually increases, as body cells are not able to process it in the required volumes, and these are the first steps to prediabetes, and then type 2 diabetes. Due to similar symptoms with other disorders, a person rarely performs a special analysis to diagnose it. As a result, a person learns about a disorder already at a serious stage of its development. Despite all the difficulties, medical therapy and hypoglycemic drugs allow you to live without fear of dangerous complications. Our Glyset review provides facts and essential information about this type 2 diabetes drug.

Indications for use

It should be said that it is impossible to completely cure type 1 and type 2 diabetes. Treatment is aimed at normalizing the patient’s condition and reducing the likelihood of complications. After all, it is they that cause great harm to health and can lead to death.

The basics of a medical course are an individual selection of a diabetic diet and the appointment of special physical activities. They are aimed at reducing weight and, accordingly, blood sugar levels. However, often these measures are not enough to bring glucose to the required range. In such cases, endocrinologists recommend taking hypoglycemic agents.

Glyset is an antidiabetic medicine developed by the American pharmaceutical company Pfizer. Endocrinologists prescribe it to patients suffering from type 2 diabetes. The drug is rapidly absorbed into the bloodstream and begins to act in a few hours. Its active substance delays the absorption of glucose in the intestines and reduces postprandial hyperglycemia. Long-term use of the drug can significantly reduce the level of glucose in the blood, stabilizing it to the required range. Glyset does not have dangerous side effects. High efficiency and safety allowed this hypoglycemic medicine to gain great popularity among doctors.

What is the composition of the drug?

Miglitol is the main active ingredient in Glyset. 1 tablet contains 25 mg, 50 mg or 100 mg of the active substance. The shell of the drug is formed by components such as povidone, magnesium stearate, and hypromellose. They are harmless and popular in pharmaceuticals.

Dosage form

Pfizer Inc. produces Glyset in the form of small round white tablets. The name of the drug is engraved on one side of the tablet, and the volume of the active substance on the other. Tablets are packed in plastic bottles, in the amount of 100 pcs.

Taking Glyset drug

How to take Glyset?

You should take Glyset before or during meals 3 times a day. Take the medicine orally with plenty of water. The therapeutic course begins with a minimum dosage of 25 mg per dose. After 4-8 weeks, the attending physician can increase the dosage to 50 mg. This is a maintenance dose for most patients. Nevertheless, 3 months after the start of taking the medicine, it is necessary to re-diagnose. The daily dosage may be increased to 100 mg 3 times a day if the level of glycosylated hemoglobin has not dropped to an acceptable range. This is the maximum permitted dose of the drug. As a clinical trial, the researchers increased the allowable dosage to 200 mg 3 times a day. Patients showed a significant decrease in blood glucose. But at the same time, the frequency of gastrointestinal upsets increased. To avoid the occurrence of side effects, do not exceed the recommended daily dosage.

The intake of fatty or high-calorie foods does not affect the hypoglycemic properties of the drug. However, alcohol is prohibited, as it can significantly change the properties of the drug. As a result, hypoglycemia or hyperglycemia may develop. Do not double the amount of medicine if you forget to take Glyset with food. You should strictly observe unit dosages without increasing them.

Side effects of Glyset

Clinical studies have shown the complete safety of Glyset when all medical recommendations are followed. However, you may experience the following side effects:

  • Stomach discomfort
  • Dizziness
  • Nausea
  • Diarrhea or constipation
  • Skin rash
  • Sweating
  • Irritability
  • Rectal bleeding

Similar symptoms are recorded in no more than 10% of patients taking Glyset. The most common cause of their occurrence is an overdose, and in rarer cases, individual intolerance to the components. If you also have the described side effects, stop taking the medicine immediately and tell your doctor about it. Only an endocrinologist can adjust your course of treatment.

Glyset contraindications


Despite its safety, Glyset has several contraindications, in which its use can be harmful to health. Tell your doctor about all chronic conditions to minimize the risks of using Glyset. An endocrinologist will not prescribe hypoglycemic drugs with the following cases:

  • Renal failure
  • Partial intestinal obstruction
  • Diabetic ketoacidosis
  • Chronic gastrointestinal upsets
  • Individual intolerance to the drug

Particular attention should be paid to pregnant and lactating women. The attending physician should establish all the negative effects of Miglitol on the child before prescribing Glyset.

Glyset Interactions

Glyset actively interacts with some groups of medicines. As a result, its hypoglycemic properties are significantly reduced. In order not to harm your health, conduct an additional consultation with your doctor. Only a specialist can correctly assess the safety of co-administration of several drugs.

How should I store the medicine?

Close the medicine vial tightly after use. This will prevent moisture from getting inside. Store Glyset in a child-proof place at a temperature of 15–30 ° C. Taking the medicine is strictly prohibited after the expiration date.

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