Duetact medication

Duetact: uses, the right dosage, and side effects

Vascular lesions, hypoglycemia, hyperglycemia, heart problems, diabetic neuropathy, and coma are just a few of the dangerous complications that diabetes causes. That is why the disease occupies a leading position among the disorders leading to the death of patients. Another danger of diabetes is its prevalence. Almost any person on the planet is at risk. The main reason for this is an unhealthy modern lifestyle, which leads to a set of extra pounds and problems with the endocrine system. Diabetes is difficult to diagnose in the early stages of development, as its symptoms are similar to non-serious diseases and people rarely seek help. Nevertheless, medicine allows you to lead a full and happy life, despite the chronic course of the disease. Observe the prescribed course of treatment and use special medicines. Duetact is one such remedy. Why is it so popular among doctors?

Indications for use Duetact

Duetact is a unique drug developed by the company Takeda Pharmaceuticals U.S.A. It consists of two hypoglycemic agents: Glimepiride and Pioglitazone Hydrochloride. Both of these components have their mechanism of action on the body, which enhances the hypoglycemic property of Duetact. Glimepiride affects the pancreas, greatly increasing insulin production. Pioglitazone at the same time enhances the sensitivity of cells to this hormone. Their simultaneous action can significantly reduce blood sugar, and the therapeutic course of administration allows you to set the glucose level within the range recommended for the patient.

Endocrinologists prescribe Duetact to patients suffering from type 2 non-insulin-dependent diabetes. The main treatment for this form of the disease is to follow a diabetic diet and perform special exercises. Doctors prescribe one hypoglycemic agent if this is not enough. In complex cases of diabetes, the sugar level does not decrease even with this treatment. In this case, doctors may prescribe Duetact. The medicine shows high efficiency in the serious course of the disease.

The composition of the drug

As we said earlier, Glimepiride and Pioglitazone Hydrochloride are two active substances of Duetact. Each pill contains 2 (or 4) mg of Glimepiride and 30 mg of Pioglitazone, respectively. The tablet shell consists of excipients such as maize starch, povidone, polyacrylic potassium, glycerol, and microcrystalline cellulose. All ingredients are safe and pose no health hazard.

What is the dosage form?

Takeda Pharmaceuticals U.S.A, Inc. produces Duetact in the form of round biconvex tablets of white color. Information on the volume of active substances is engraved on one side of the tablet. The tablets are packaged in plastic bottles. Their number is different.

Duetact using

How to take Duetact?

It is necessary to consult a specialist before using the medicine. Only an experienced attending physician can prescribe the right course of treatment and choose the exact dose. The patient should take a daily dose of Duetact during the main meal.. Take the drug orally with plenty of water. In this case, the initial dosage is 30mg / 2 mg. After you start using the medicine, you need to measure blood glucose levels. If necessary, the attending physician can increase the daily dosage to 30mg / 4 mg.

If you have missed taking Duetact, you should not double it during the next use. The dosage should always be one. The intake of fatty or high-calorie foods does not affect the hypoglycemic properties of the drug. However, alcohol is not recommended because it can negatively affect sugar levels.

Remember, exceeding the recommended daily dosage is strictly prohibited. An overdose of Duetact can cause life-threatening hypoglycemia, which can lead to death.


Duetact is a highly effective medicine that is well suited to lowering high blood sugar. The drug has some contraindications, in which its use is prohibited. Your doctor will not prescribe a combination drug if you have:

  • Heart failure
  • Bladder cancer
  • Diabetic ketoacidosis
  • Eye problems
  • Serious liver or kidney disease
  • Individual intolerance to components

It is very important to report all chronic disorders to your doctor. Only a complete medical history will allow the doctor to prescribe Duetact or another hypoglycemic drug.

Women should be especially careful. Taking Duetact during pregnancy and lactation can negatively affect the baby. Therefore, only the attending physician will be able to assess all the risks and prescribe medicine. Besides, taking Duetact can cause ovulation and, consequently, an unwanted pregnancy.

Duetact side effects

What are the possible side effects?

Clinical studies have shown that Duetac is safe to use by people who have no contraindications. Nevertheless, about 5% of the total number of patients had certain side effects. They are not life-threatening but can affect the course of treatment. Most often, endocrinologists record the following symptoms:

  • Swelling
  • Nausea
  • Headache
  • Anxiety
  • Depression
  • Cardiopalmus
  • Pain in the bladder
  • Chills
  • Unusual fatigue

In the event of such symptoms, you should immediately stop taking Duetact. Seek help from a doctor. The endocrinologist will lower the daily dosage, or prescribe a more suitable hypoglycemic drug.

Drug interaction

Duetac actively interacts with other medicines. The attending physician should prescribe it with caution in conjunction with other drugs. Otherwise, additional health problems may arise.

Storage conditions

Duetac should be protected from moisture, light and stored at room temperature. Keep the bottle tightly closed. Children and pets should not have access to medicine. And remember, an expired Duetact is strictly forbidden to use.

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